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GLP-1 receptor agonists significantly lowered CRP levels (standardised mean difference of 0.39) and TNF- levels (SMD of 0.51), with longer treatment durations yielding more noticeable benefits, according to a thorough meta-analysis published in 2025 that synthesised 25 studies involving 1,878 patients with type 2 diabetes
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GLP1s assist in reducing high blood pressure, high cholesterol, diabetes and lead to a reduced risk of cardiovascular diseases such as heart attacks and strokes
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